Maine Restaurant’s Lasagna Ranked No. 2 Best in America

Lovefood is a popular food platform known for recipes, cooking guides, restaurant reviews, food news, and our favorite. food rankings and lists.

So when they set out to find the best lasagna spot in every state, we had to see which Maine restaurant earned the honors.

Maine has plenty of incredible places to grab a delicious meal, but one destination rose above the rest, ranking 2nd best in the entire country! Impressive stuff.

For Maine food lovers, sometimes the best meals are worth the drive, and Isa Bistro in Portland is making a strong case for a road trip south. This cozy restaurant recently gained national attention for its incredible lasagna, earning a spot among the best in America.

Isa Bistro is the kind of place that makes a trip to Portland feel even more of a good time. Chef Isaul Perez puts a creative spin on classic comfort food, and the restaurant’s eggplant lasagna has become a must-try dish for anyone who appreciates a great meal.

This isn’t your average lasagna. Isa’s version takes a familiar favorite and elevates it with layers of flavor, seasonal ingredients, and the kind of attention to detail that has helped the restaurant build a loyal following. It’s the perfect example of why Maine’s food scene continues to earn national recognition.

Beyond the lasagna, Isa Bistro offers a seasonal menu filled with handmade pastas, creative small plates, and dishes that showcase the restaurant’s unique style. The atmosphere is a relaxed, welcoming vibe, and exactly the kind of spot you hope to find after a day exploring Portland.

Isa Bistro is located at 79 Portland St. Dinner is served Monday, Wednesday, Thursday, and Sunday from 4 p.m. to 9 p.m. The restaurant is closed Tuesdays. Friday and Saturday hours include brunch from 11:30 a.m. to 3:30 p.m., followed by dinner service.

For Maine foodies in Bangor and beyond, Isa Bistro is a destination worth adding to your dining bucket list, especially if a nationally recognized lasagna is waiting at the end of the drive.

@mackenziemfritz Isa bistro - portland, maine. Pro-tip go there for lunch (only lunch on fridays) and eat on their patio. Or go for dinner, I promise you will become obsessed. #portlandmainefood #portlandmainerestaurants #portlandmainefoodie #isabistro ♬ If You Love Me - The Informers